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Pipeline
Nilofabicin
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Indication
MRSA (Methicillin-resistant Staphylococcus aureus)
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Development stage
- Nilofabicin met all efficacy endpoints in a U.S. Phase 2 clinical study for treatment of MRSA.
Nilofabicin
Nilofabicin's differentiation
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01
Specific inhibition of the Fab l target, which is expressed only in the S. aureus family group
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02
기존의 MRSA용 항생제들이 보이는 내성 및 다양한 부작용 없음
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03
Showed superior non-clinical efficacy results when compared to top MRSA drugs Zyvox and Cubicin
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04
U.S. Phase 2 clinical study results showed a 91 percent cure rate in MRSA patients within three days and a 100 percent cure for all MRSA patients within two weeks
Fab I (Fatty acid biosynthesis I)
- Enoyl-acyl carrier protein reductase is present in bacteria. This protein holds a vital role regarding bacterial fatty acid synthesis and is essential for survival.
- When Fab I is suppressed using Nilofabicin, MRSA strains are selectively killed to treat infectious diseases without side effects to the human body.